Macrocyclic peptide therapeutics

for safer targeted medicine

Macrocyclic peptide therapeutics

for safer targeted medicine

Macrocyclic peptide therapeutics

for safer targeted medicine

Dysruptx is developing precision therapeutics designed to treat human disease while reducing off-target toxicity through a targeted and selective approach.

Dysruptx is developing precision therapeutics designed to treat human disease while reducing off-target toxicity through a targeted and selective approach.

Dysruptx is developing precision therapeutics designed to treat human disease while reducing off-target toxicity through a targeted and selective approach.

Naturally precise by design

Naturally precise by design

Naturally precise by design

Naturally precise by design

Protein–protein interactions have evolved over millions of years to achieve remarkable specificity within complex biological systems.

Protein–protein interactions have evolved over millions of years to achieve remarkable specificity within complex biological systems.

Mapping the interface

Mapping the interface

Mapping the interface

Mapping the interface

Dysruptx starts with these naturally evolved interaction sites to identify highly relevant binding patterns from the outset.

Dysruptx starts with these naturally evolved interaction sites to identify highly relevant binding patterns from the outset.

Designing Dysruptors

Designing Dysruptors

Designing Dysruptors

Designing Dysruptors

From this interface knowledge, Dysruptx develops macrocyclic peptide Dysruptors engineered to mimic and disrupt disease-relevant interactions with precision.

From this interface knowledge, Dysruptx develops macrocyclic peptide Dysruptors engineered to mimic and disrupt disease-relevant interactions with precision.

Selectivity from the start

Selectivity from the start

Selectivity from the start

Selectivity from the start

By addressing off-target toxicity early in discovery, Dysruptx supports a more selective and potentially safer path for targeted therapeutic development.

By addressing off-target toxicity early in discovery, Dysruptx supports a more selective and potentially safer path for targeted therapeutic development.

We’re developing precision macrocyclic peptide therapeutics designed to treat human disease while reducing off-target toxicity from the earliest stages of discovery.

IT'S FREE

Connect with us

We’re developing precision macrocyclic peptide therapeutics designed to treat human disease while reducing off-target toxicity from the earliest stages of discovery.

IT'S FREE

Connect with us

We’re developing precision macrocyclic peptide therapeutics designed to treat human disease while reducing off-target toxicity from the earliest stages of discovery.

IT'S FREE

Connect with us

Who we are

About Dysruptx

About Dysruptx

Dysruptx is a Glasgow-based biotechnology company developing precision macrocyclic peptide therapeutics designed to reduce off-target toxicity and improve the safety of targeted medicines.

Dysruptx is a Glasgow-based biotechnology company developing precision macrocyclic peptide therapeutics designed to reduce off-target toxicity and improve the safety of targeted medicines.

Focus areas

Focus areas

Oncology, inflammation, immunology

Oncology, inflammation, immunology

A young person with curly hair smiles at the camera while sitting in front of a laptop against a dark background.

Selective binding

Protein targeting

A young person with curly hair smiles at the camera while sitting in front of a laptop against a dark background.

Selective binding

Protein targeting

A more precise approach to therapeutic discovery

Focused on improving selectivity and reducing off-target toxicity from the earliest stages.

Precision-led

Designing therapeutics with selectivity built in from the start

Mechanism-driven

Grounded in protein–protein interaction biology to guide discovery

Early risk reduction

Addressing off-target toxicity at the discovery stage, not later

Platform-enabled

Combining therapeutic development with scalable partnership opportunities

A more precise approach to therapeutic discovery

Focused on improving selectivity and reducing off-target toxicity from the earliest stages.

Precision-led

Designing therapeutics with selectivity built in from the start

Mechanism-driven

Grounded in protein–protein interaction biology to guide discovery

Early risk reduction

Addressing off-target toxicity at the discovery stage, not later

Platform-enabled

Combining therapeutic development with scalable partnership opportunities

A more precise approach to therapeutic discovery

Focused on improving selectivity and reducing off-target toxicity from the earliest stages.

Precision-led

Designing therapeutics with selectivity built in from the start

Mechanism-driven

Grounded in protein–protein interaction biology to guide discovery

Early risk reduction

Addressing off-target toxicity at the discovery stage, not later

Platform-enabled

Combining therapeutic development with scalable partnership opportunities